Hirzel H O, Nuesch K, Luetolf U M, Gruentzig A, Horst W, Krayenbuehl H P
Arch Mal Coeur Vaiss. 1980 Jun;73(6):651-9.
40 patients underwent aortocoronary bypass surgery for coronary artery disease involving a single vessel in 2 cases, 2 vessels in 10 cases, and all 3 vessels in 28 cases. Preoperative exercise Thallium 201 scanning showed one or several zones of hypofixation (80 p. 100 of maximum myocardial fixation) which were not present at rest. After surgery, exercise scanning was normal in 22 out of 24 patients with normalised or improved vascularisation on control angiography, but remained pathological in 2 cases. However, comparable areas of hypoperfusion were observed in 16 patients with no improvement or worsening of vascularisation after operation. The exercise EG remained pathological in 6 out of 24 patients with normalised or improved vascularisation and in 11 out of 16 patients with identical or worsened vascularisation. In addition, 10 of the 24 patients with improved or normalised vascularisation, and 12 of 16 patients with identical or worsened vascularisation, continued to have chest pain after operation. A zone of hypoactivity was observed in the preoperative exercise scan in 18 out of 20 patients with isolated stenosis treated by catheter dilatation. Normalised exercise scans were recorded in all patients in the month following dilatation, but the exercise ECG remained pathological in 3 patients. In conclusion, 201 Thallium scanning gives a good assessment of myocardial vascularisation after revascularisation procedures. It helps identify patients with non-anginal post-operative chest pain, and detects residual ischaemia in patients without ischaemic signs on electrocardiography.
40例患者因冠状动脉疾病接受了主动脉冠状动脉搭桥手术,其中2例为单支血管病变,10例为2支血管病变,28例为3支血管病变。术前运动铊201扫描显示一个或几个低摄取区(最大心肌摄取的80%),静息时不存在。手术后,24例血管造影显示血管化正常或改善的患者中,22例运动扫描正常,但2例仍为病理性。然而,16例术后血管化无改善或恶化的患者中观察到类似的灌注不足区域。24例血管化正常或改善的患者中有6例运动心电图仍为病理性,16例血管化相同或恶化的患者中有11例运动心电图仍为病理性。此外,24例血管化改善或正常的患者中有10例,16例血管化相同或恶化的患者中有12例术后仍有胸痛。在20例接受导管扩张治疗的孤立性狭窄患者中,18例术前运动扫描出现低活性区。扩张后一个月所有患者运动扫描均正常,但3例患者运动心电图仍为病理性。总之,铊201扫描能很好地评估血运重建术后的心肌血管化。它有助于识别术后非心绞痛性胸痛患者,并检测心电图无缺血迹象患者的残余缺血情况。