Cavallini L, Marchi S, Spisni L, Li Calzi M
Arch Sci Med (Torino). 1980 Jan-Mar;137(1):13-22.
The various components of the normal intestinal immunological system have been examined, i.e. immunocompetent cells (isolated and in clusters) and humoral factors. The modifications observed in this system during ulcerous colitis are then analysed, mention being made of the various pathogenetic interpretations that have been put forward to explain this condition. The pharmacology and action mechanism of DSCG are then examined. This drug has been in use for some years in the treatment of a number of extraintestinal and immuno-allergic based conditions and, recently, of some enteropathis attributed to food allergies. The reported results of using DSCG in ulcerous colitis are then reviewed. They would appear to be fairly encouraging.
已对正常肠道免疫系统的各种组成部分进行了检查，即免疫活性细胞（分离的和成簇的）和体液因子。然后分析了在溃疡性结肠炎期间该系统中观察到的变化，并提及了为解释这种情况而提出的各种发病机制解释。接着研究了色甘酸钠（DSCG）的药理学和作用机制。这种药物已经用于治疗多种肠道外和基于免疫过敏的病症数年，最近还用于治疗一些归因于食物过敏的肠道疾病。然后回顾了在溃疡性结肠炎中使用DSCG的报告结果。这些结果似乎相当令人鼓舞。
