Valcurone G, Brugo M A, Tassi G C
Boll Ist Sieroter Milan. 1980;59(3):173-97.
A comprehensive picture of the most well-known immunomodulators has been drawn, focussing the attention on their immunopharmacological profile and their prospective clinical use. Besides, the cell targets of the immunologically active agents are also considered. The role of cyclic nucleotides in the mechanisms of immune regulation as well as the importance of the host characteristics in this connection are carefully analyzed. Some general considerations are finally set forth on the usefulness of the immunopharmacology investigation both in defining the action of the agents under study and in suggesting their potential role in the design of new agents for immunotherapy.
