Morosini P P, Carletti P, Campanella N, Ferretti G F
Boll Soc Ital Biol Sper. 1980 Jun 30;56(12):1243-7.
The effects of exogenous GnRH on plasma FSH and LH concentrations were evaluated in 12 patients with pituitary macroadenomas and in 11 patients with pituitary microadenomas. In patients of the former group the mean values of FSH were not increased as compared with healthy controls, while LH was significantly lower. In patients of the latter group FSH was strongly greater than in normal controls, while serum LH concentrations were included in the normal range. These findings suggest that the exaggerated response of FSH can be useful to the diagnosis of the pituitary microadenomas.
对12例垂体大腺瘤患者和11例垂体微腺瘤患者评估了外源性促性腺激素释放激素（GnRH）对血浆促卵泡激素（FSH）和促黄体生成素（LH）浓度的影响。在前一组患者中，与健康对照组相比，FSH的平均值没有升高，而LH则显著降低。在后一组患者中，FSH明显高于正常对照组，而血清LH浓度在正常范围内。这些发现表明，FSH的过度反应可能有助于垂体微腺瘤的诊断。
