Meyer J E, Silverman P, Gandbhir L
Arch Surg. 1978 Jul;113(7):801-5. doi: 10.1001/archsurg.1978.01370190023003.
Fat necrosis of the breast is an uncommon entity but may mimic malignancy on both mammographic and clinical examination. Seven patients had recent excisional breast biopsy specimens that showed fat necrosis. The mammographic appearance is a reflection of the reparative phase of the lesion, with a cystic appearance representing early or incomplete healing. Progression to connective tissue invasion appears as an irregular, dense, spiculated mass. Clinically, these tumors may be firm, fixed, and produce overlying skin or nipple retraction. No matter how strong the clinical suspicion that a breast lesion represents fat necrosis, an excisional biopsy is necessary for confirmation in all cases.
乳腺脂肪坏死是一种不常见的病症，但在乳房X线摄影和临床检查中可能会被误诊为恶性肿瘤。7例患者近期接受了乳腺切除活检，病理显示为脂肪坏死。乳房X线摄影表现反映了病变的修复阶段，囊性表现代表早期或不完全愈合。进展为结缔组织浸润时则表现为不规则、致密、有毛刺的肿块。临床上，这些肿瘤可能质地坚硬、固定，并导致皮肤或乳头回缩。无论临床上对乳腺病变为脂肪坏死的怀疑有多强烈，所有病例都需要进行切除活检以确诊。
