[Induction of respiratory defect as a function of energy metabolism regulation (author's transl)].

Metabolic disturbances can often be inferred from the regulation kinetics of glycolysis and energy metabolism. A short oxygen deficit leads to an irreversible change in the regulation system of yeast cells which results in a lower energy level for the cell. At the same time a higher "respiratory defect" mutation rate is also observed. These mutants are manifested by a glycogen deficiency. Furthermore, the entire glycolysis regulation is disturbed. Since these cells sometimes behave like tumour cells, this mutation induction is considered to be one of the molecular biological aspects of the regulation defect.