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氯丙嗪对妊娠大鼠血浆皮质酮、促性腺激素和催乳素浓度的影响(作者译)

[Chlorpromazine effect on plasma concentration of corticosterone, gonadotropins and prolactin in the pregnant rat (author's transl)].

作者信息

Lescoat G, Chambon Y

出版信息

Ann Endocrinol (Paris). 1980 Mar-Apr;41(2):119-25.

PMID:6781402
Abstract

Plasma corticosterone, gonadotropins and prolactin are measured from day 1 (G1) to day 4 (G4) of gestation in normal or chlorpromazine injected rats. Chlorpromazine induces a modification of plasma corticosterone, gonadotropins and prolactin (increase in corticosterone and prolactin at G1, p less than 0,001 or P less than 0,01; decrease in LH at G2, p less than 0,01; no modification of FSH). Differed implantations by chlorpromazine seems to be due to an increase in plasma corticosterone and prolactin at G1 and a decrease in plasma LH at G2.

摘要

在正常或注射氯丙嗪的大鼠中,于妊娠第1天(G1)至第4天(G4)测量血浆皮质酮、促性腺激素和催乳素。氯丙嗪会引起血浆皮质酮、促性腺激素和催乳素的变化(G1时皮质酮和催乳素增加,p<0.001或P<0.01;G2时促黄体生成素降低,p<0.01;促卵泡生成素无变化)。氯丙嗪导致的植入差异似乎是由于G1时血浆皮质酮和催乳素增加以及G2时血浆促黄体生成素降低。

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Ann Endocrinol (Paris). 1980 Mar-Apr;41(2):119-25.
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