Samgina A A, Ermilova V D
Arkh Patol. 1978;40(4):52-9.
During 22 years (1955--1976) in the Department of Endocrinology of the Oncological Research Center of the USSR AMS 2953 patients were treated for primary mammary cancer, 87 (2.9%) of them developed bilateral mammary cancer. The differential diagnosis of primary and metastic cancer was based on the combination of clinical and morphological data: the extent and stage of the process in both mammary glands, localization of tumor nodes, duration of the interval between the development of cancer in the first and the second mammary gland, the absence of relapses and metastases after treatment of the first carcinoma and during a year after the second mastectomy, the degree of malignancy of the tumors, invasion of blood and lymph vessels of the gland and the background against which the tumor had developed.
在苏联医学科学院肿瘤研究中心内分泌科的22年（1955 - 1976年）里，2953例患者接受了原发性乳腺癌治疗，其中87例（2.9%）发生了双侧乳腺癌。原发性癌与转移性癌的鉴别诊断基于临床和形态学数据的综合判断：双侧乳腺病变的范围和阶段、肿瘤结节的定位、第一侧和第二侧乳腺癌症发生之间的间隔时间、第一例癌治疗后及第二例乳房切除术后一年内无复发和转移情况、肿瘤的恶性程度、腺体血管和淋巴管的侵犯情况以及肿瘤发生的背景。
