促甲状腺激素释放激素生物活性代谢产物环（组氨酸-脯氨酸）的特异性放射免疫测定法。
Specific radioimmunoassay of cyclo (His-Pro), a biologically active metabolite of thyrotropin-releasing hormone.
作者信息
Mori M, Prasad C, Wilber J F
出版信息
Endocrinology. 1981 May;108(5):1995-7. doi: 10.1210/endo-108-5-1995.
PMID:6783397
Abstract
We have developed a radioimmunoassay that can detect 10 pg cyclo (His-Pro) in rat brain perchloric acid extracts. The normal rat brain concentration of cyclo (His-Pro) ranged from 35-61 pmole/brain. The elution profiles of cyclo (His-Pro)-like immunoreactivity and radioactive cyclo (His-Pro) following gel filtration and ion-exchange chromatography were similar.
摘要
我们已经开发出一种放射免疫分析法，该方法能够检测大鼠脑高氯酸提取物中10皮克的环（组氨酸-脯氨酸）。环（组氨酸-脯氨酸）在正常大鼠脑中的浓度范围为35 - 61皮摩尔/脑。经凝胶过滤和离子交换色谱法后，环（组氨酸-脯氨酸）样免疫反应性和放射性环（组氨酸-脯氨酸）的洗脱曲线相似。
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