Blaha H, Karg O, Cujnik F
MMW Munch Med Wochenschr. 1981 Feb 20;123(8):289-94.
Eight cases of endothoracal carcinoma associated with pulmonary fibrosis or with interstitial pneumonia are reported. The interstitial pneumonia and the fibrosis and carcinoma are confirmed in all cases. Statements on incidence cannot be made: they are more or less random observations in recent years. There are, however, grounds for supposing that this coincidence is by no means rare. Problems arise in differential diagnosis and the decision to operate, for irradiation therapy and for chemotherapy. The question of a possible causal connection, whether in the sense of a paraneoplasia or of cancer development due to previous damage to the lung is left open.
本文报告了8例伴有肺纤维化或间质性肺炎的胸内癌病例。所有病例均确诊为间质性肺炎、纤维化及癌症。由于这些病例或多或少是近年来的随机观察,因此无法给出发病率的相关陈述。然而,有理由推测这种巧合绝非罕见。在鉴别诊断以及决定是否进行放疗和化疗时会出现问题。关于是否存在可能的因果关系,无论是副肿瘤综合征意义上的,还是由于先前肺部损伤导致癌症发生的,目前尚无定论。