[Allergization of the organism by Neisseria meningitidis. II. studies concerning the results of vaccine therapy in diseases caused by bacterial allergy (author's transl)].

A three years' study was performed regarding the influencing of vaccine therapy in 360 patients affected with diseases caused by bacterial allergy. An evaluation was made concerning the effects obtained by treatment with autovaccines in 110 patients, with stock vaccines in 60 patients, with autovaccines enriched with strain Neisseria meningitidis (N.m) in 60 patients, and with stock vaccines enriched with N.m. in 130 patients. N.m. was added to the vaccines because of its highly positive reaction in skin tests and its frequent occurrence in asthma patients (15.45%). A possible allergization of the organism by this microorganism was studied. A comparison between the final therapeutical results showed statistically far better treatment results through autovaccines enriched with N.m. (74.9%) in contrast to treatment with autovaccines where the percentage amounted to 71.7%, with stock vaccines to 64.9%, and stock vaccines enriched with N.m. to 64.6%. Our studies led to the suggestion that more attention should be paid to the presence of N.m. in patients affected with diseases caused by bacterial allergy and that studies on a possible contribution of the above microorganism in the sensibilization of the organism should be continued.