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Immunologic studies of factor IX (Christmas factor). II. Immunoradiometric assay of factor IX antigen.

作者信息

Yang H C

出版信息

Br J Haematol. 1978 Jun;39(2):215-24. doi: 10.1111/j.1365-2141.1978.tb01091.x.

DOI:10.1111/j.1365-2141.1978.tb01091.x
PMID:678474
Abstract

A solid-phase two-site immunoradiometric assay has been developed which measures factor IX antigen levels as low as 0.0004 u per ml of plasma. In normal individuals, the factor IX antigen level correlated with the factor IX procoagulant level. In haemophilia B, 14 patients had markedly reduced antigen levels (less than 0.06 u/ml) and five had normal levels (greater than 0.60 u/ml).

摘要

相似文献

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引用本文的文献

1
Physiological levels of blood coagulation factors IX and X control coagulation kinetics in an in vitro model of circulating tissue factor.生理水平的凝血因子 IX 和 X 控制着循环组织因子体外模型中的凝血动力学。
Phys Biol. 2013 Jun;10(3):036003. doi: 10.1088/1478-3975/10/3/036003. Epub 2013 Apr 15.
2
Combined functional and immunochemical analysis of normal and abnormal human factor X.正常与异常人凝血因子X的联合功能及免疫化学分析
J Clin Invest. 1979 Oct;64(4):884-94. doi: 10.1172/JCI109554.