[Effects of gangliosides on the in vitro growth of cultured spinal ganglia of guinea pigs. Preliminary results on a preparation of gangliosides from the cerebral cortex of cattle].

Brain bovine gangliosides added for 48 hrs. to the culture medium at concentrations ranging from 5.10(-5) mg/ml to 5.10(-7) mg/ml induced a statistically significant (p less than .005 to p less than 000,5) increase of the number of neurites of the outgrowth zone of guinea-pig spinal ganglia. On the contrary, the neurite length was only slightly increased.