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[果蝇精子中烷基化化合物诱导的突变分析。II. 黑腹果蝇中化学诱导的不稳定基因座状态的性质]

[Analysis of the mutations induced by alkylating compounds in Drosophila sperm. II. The nature of the chemically induced unstable locus states in Drosophila melanogaster].

作者信息

Aslanian M M, Smirnova V A

出版信息

Genetika. 1981;17(4):684-93.

PMID:6785155
Abstract

Two types of unstable visible mutations induced by ethylnitrosourea and ethylmethanesulfonate were detected and studied. In cases of replicating instability, mutations newly emerging in the offspring of a single male were allelic. They were located either in a single site or in different sites of the gene. Substitution of autosomes in unstable lines was followed by stabilization of both normal and mutant phenotype in two cases of replicating instability.

摘要

检测并研究了由乙基亚硝基脲和甲磺酸乙酯诱导产生的两种类型的不稳定可见突变。在复制不稳定的情况下,单个雄性后代中新出现的突变是等位基因。它们位于基因的单个位点或不同位点。在不稳定品系中替换常染色体后,在两例复制不稳定的情况下,正常和突变表型均趋于稳定。

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