Aikawa M, Yoshida N, Nussenzweig R S, Nussenzweig V
J Immunol. 1981 Jun;126(6):2494-5.
Pb44, the protective antigen of rodent malaria sporozoite (Plasmodium berghei) covers the entire surface of mature, salivary gland sporozoites. This antigen is undetectable in approximately 50% of the immature, i.e., oocyst sporozoites. On the surface of the remaining oocyst sporozoites, Pb44 is found in patches. Pb44 is present in early exoerythrocytic liver stages of P. berghei but is present in early exoerythrocytic liver stages of P. berghei but becomes undetectable after 30 hr of intrahepatocytic development. It seems likely that Pb44 is a differentiation antigen associated with an unique function of the sporozoites, perhaps penetration in the target host cells.
Pb44是啮齿类疟原虫（伯氏疟原虫）的保护性抗原，覆盖成熟唾液腺子孢子的整个表面。在大约50%的未成熟卵囊子孢子中检测不到这种抗原。在其余卵囊子孢子的表面，Pb44呈斑块状分布。Pb44存在于伯氏疟原虫的早期红细胞外期肝脏阶段，但在肝细胞内发育30小时后就检测不到了。Pb44似乎是一种与子孢子独特功能相关的分化抗原，可能与穿透靶宿主细胞有关。
