Ackenheil M, Engel R R
MMW Munch Med Wochenschr. 1981 May 8;123(19):805-8.
Starting from the consideration that the assumed disturbances of the limbic system in psychiatric patients must lead, among other things, to functional autonomic disorders, the physiological reactions of previously untreated depressive and schizophrenic patients to short-lasting experimental stress situations were compared with those of healthy subjects. Whereas the plasma catecholamine levels and the autonomic functions of healthy subjects were easily foreseeable and reacted adequately to the situation, the two groups of patients showed a high degree of general unspecific activation even, eg in resting situations, associated with a relatively slight reaction to stress situations. How far these findings are of significance in the clarification of therapeutic methods in those patients exposed to increased stress is discussed.
基于这样一种考虑,即假定精神病患者边缘系统的紊乱必定会导致功能性自主神经紊乱等情况,将未经治疗的抑郁症患者和精神分裂症患者在短时间实验应激情况下的生理反应与健康受试者的生理反应进行了比较。健康受试者的血浆儿茶酚胺水平和自主神经功能易于预测且能对该情况做出适当反应,而两组患者即使在静息状态下也表现出高度的一般性非特异性激活,对应激情况的反应相对轻微。文中讨论了这些发现对于阐明那些处于应激增加状态的患者的治疗方法具有多大意义。