[Conditions for the development of auto-oscillations in the hematopoietic system].

Oscillations occur when the time of delay in the feed-back chain is increased or when the control system of hemopoiesis is "roughened". The analysis of clinical and experimental material indicates that initiation of oscillations seems not to be connected with cell interaction in the bone marrow; it is determined by the feed-back chain from the periphery to the hemopoietic organs. As the same time the role of intercellular interactions is essential for the transfer of autooscillations, initiated in some branches of hemopoiesis, to its other shoots. Oscillations in hemopoiesis with a period of three weeks or more recorded sometimes in humans are evidently initiated in the myeloid shoots, while the oscillations with the period of one and a half--two years--in the erythroid one.