Lynch C, Pont A, Weingarden S I
Arch Phys Med Rehabil. 1981 Jun;62(6):291-3.
Heterotopic ossification (HO), reported to occur in 20% to 40% of spinal cord injured patients, has been described in the hips, knees, shoulders and elbows, but not in the hands or around the phalangeal joints. This report is believed to be the first of HO of the hand after spinal cord injury. Nine weeks after injury, a diving accident, a 27-year-old man having C6 quadriplegia, motor complete, sensory incomplete, developed acute swelling and loss of range of motion in both hands. Serum alkaline phosphatase showed no significant rise. Bone scan demonstrated increased uptake in many joints of the left hand with x-rays remaining normal. Repeat films three weeks later demonstrated calcific densities adjacent to the midshaft of the proximal phalanx of the left finger. Twice daily range of motion of the hand resulted in improved range of motion. the etiology of HO in spinal cord injured patients remains unknown, and we have no explanation of its occurrence in the hands of this patient.
异位骨化（HO）据报道发生在20%至40%的脊髓损伤患者中，已在髋部、膝部、肩部和肘部被描述，但未见于手部或指关节周围。本报告据信是脊髓损伤后手HO的首例报道。一名27岁男性因潜水事故致伤，损伤九周后出现C6级四肢瘫，运动完全性损伤，感觉不完全性损伤，双手出现急性肿胀和活动范围丧失。血清碱性磷酸酶无显著升高。骨扫描显示左手多个关节摄取增加，而X线片仍正常。三周后复查X线片显示左手近端指骨中轴附近有钙化密度影。手部每天进行两次活动范围训练后活动范围得到改善。脊髓损伤患者HO的病因尚不清楚，我们也无法解释该患者手部为何会出现HO。
