Burleson J L, Peyton G R, Glaze W H
Bull Environ Contam Toxicol. 1978 Jun;19(6):724-8. doi: 10.1007/BF01685864.
Previous work has shown that 3, 5-dibromotyrosine acts as a thyroxine production/secretion inhibitor which may imply a similar response to chlorotyrosine derivatives. Chloro- and dichlorotyrosine have been produced in the laboratory by the action of aqueous chlorine upon tyrosine at low pH, and have been found in the effluent from superchlorination facilities in use at three municipal waste treatment plants. The extent to which these and other possible chlorinated amino acids occur in superchlorinated waste products, and their fate in receiving streams is not known, and is under investigation by this laboratory.
先前的研究表明,3,5-二溴酪氨酸可作为甲状腺素生成/分泌抑制剂,这可能意味着对氯酪氨酸衍生物有类似反应。氯酪氨酸和二氯酪氨酸已在实验室中通过在低pH值下用氯水作用于酪氨酸而制得,并已在三个城市污水处理厂使用的超氯化设施的流出物中发现。这些以及其他可能的氯化氨基酸在超氯化废物产物中的存在程度及其在接收水体中的归宿尚不清楚,本实验室正在对此进行研究。