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Serum albumin beads: an injectable, biodegradable system for the sustained release of drugs.

作者信息

Lee T K, Sokoloski T D, Royer G P

出版信息

Science. 1981 Jul 10;213(4504):233-5. doi: 10.1126/science.6787705.

Abstract

Biologically active compounds were entrapped in cross-linked serum albumin microbeads. Injection of these drug-impregnated beads into rabbits produced no adverse immunological reactions. Sustained release (20 days) of progesterone was demonstrated in vivo.

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