Breyer D, Cvitković P, Skrabalo Z, Pedersen O, Rocić B
J Clin Endocrinol Metab. 1981 Sep;53(3):654-5. doi: 10.1210/jcem-53-3-654.
Insulin binding to specific erythrocyte receptors was investigated in group of 25 subjects with Klinefelter's syndrome (47 XXY genotype) and 14 healthy male volunteers. Insulin binding was significantly decreased in Klinefelter subjects (P less than 0.01 at insulin concentrations of 0.051 and 0.136 mmol/liter); however, their fasting glucose concentration was normal (87 +/- 17), and the glucose disappearance rate was slightly increased (2.3 +/- 0.9; P less than 0.2). These data indicated a compensatory, mechanism involved in the glucose metabolism in Klinefelter's syndrome.
对25名患有克兰费尔特综合征（47 XXY基因型）的受试者和14名健康男性志愿者进行了胰岛素与特定红细胞受体结合情况的研究。克兰费尔特综合征患者的胰岛素结合显著降低（在胰岛素浓度为0.051和0.136毫摩尔/升时，P<0.01）；然而，他们的空腹血糖浓度正常（87±17），葡萄糖消失率略有增加（2.3±0.9；P<0.2）。这些数据表明克兰费尔特综合征患者的葡萄糖代谢存在一种代偿机制。
