Use of alpha-methylphenylalanine for studies of brain development in experimental phenylketonuria.
作者信息
Huether G, Neuhoff V
出版信息
J Inherit Metab Dis. 1981;4(2):67-8. doi: 10.1007/BF02263594.
PMID:6790851
Abstract
Experimental phenylketonuria was induced in newborn rats by administration of L-phenylalanine and alpha-methylphenylalanine. There was no primary disturbance of myelination, but reduced cell proliferation, early cell death and compensatory hyperplasia were evident in the cerebellum.
摘要
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