Ruitenbeek W, Sengers R C, Trijbels J M, Stadhouders A M, Janssen A J
J Inherit Metab Dis. 1981;4(2):91-2. doi: 10.1007/BF02263606.
A method is presented for the in vitro testing of the energy metabolism of human skeletal muscle. The levels of creatine phosphate, ATP, ADP and AMP, which are defined by the activity of many enzyme system, are measured after incubation of the muscle homogenate with various substrates in the presence or absence of specific inhibitors. Detection of abnormal metabolite concentrations is important for diagnosis of patients with myopathic syndromes.
本文介绍了一种用于体外检测人体骨骼肌能量代谢的方法。在肌肉匀浆与各种底物一起孵育后，在有或没有特定抑制剂的情况下，测量由许多酶系统的活性所决定的磷酸肌酸、三磷酸腺苷（ATP）、二磷酸腺苷（ADP）和一磷酸腺苷（AMP）的水平。检测代谢物浓度异常对于诊断患有肌病综合征的患者很重要。
