Parkin J L
Otolaryngol Head Neck Surg. 1981 May-Jun;89(3 Pt 1):376-80. doi: 10.1177/019459988108900304.
Otitis media continues to be one of the most common diagnoses made in the offices of family physicians, pediatricians, and otolaryngologists. The emergence of ampicillin resistant Hemophilus influenzae as an important etiologic agent for otitis media has altered the selection of a therapeutic antimicrobial drug. This article reviews the role of the penicillins, cephalosporins, and sulfonamides in the treatment of otitis media. Amoxicillin continues to be the drug chosen for the uncultured otitis media. Backup drugs for use in unresponsive cases include trimethoprim-sulfamethoxazole, erythromycin-sulfisoxazole, and cefaclor. The cost of the drug should be a factor in the selection when efficacy is equal.
中耳炎仍然是家庭医生、儿科医生和耳鼻喉科医生诊所中最常见的诊断之一。耐氨苄青霉素的流感嗜血杆菌作为中耳炎的一种重要病原体的出现，改变了治疗性抗菌药物的选择。本文综述了青霉素、头孢菌素和磺胺类药物在中耳炎治疗中的作用。阿莫西林仍然是未培养出病原体的中耳炎的首选药物。用于治疗无反应病例的备用药物包括甲氧苄啶-磺胺甲恶唑、红霉素-磺胺异恶唑和头孢克洛。当疗效相同时，药物成本应作为选择药物的一个因素。
