生育能力正常与生育能力低下男性的内分泌功能及精液分析比较

A comparison of endocrine function and semen analysis in fertile and subfertile men.

作者信息

Gray P, Franken D R, Slabber C F, Potgieter G M

出版信息

Andrologia. 1981 May-Jun;13(3):260-4. doi: 10.1111/j.1439-0272.1981.tb00046.x.

DOI:10.1111/j.1439-0272.1981.tb00046.x

Abstract

We studied 122 normozoospermic, 62 oligozoospermic and 22 azoospermic patients and compared serum testosterone, LH and FSH with semen analysis. Testosterone was similar in all three groups studied. FSH rose significantly in the oligozoospermic and azoospermic groups (p less than 0.01). LH was similar in the normozoospermic and oligozoospermic groups but rose significantly in the azoospermic group (p less than 0,01). The rise in FSH is in accordance with the theory of inhibin release during the maturation states of spermatogenesis. The rise in LH might indicate a separate feedback mechanism mediated by the early stages of spermatogenesis and not by testosterone alone.

摘要

我们研究了122例精子正常、62例少精子症和22例无精子症患者，并将血清睾酮、促黄体生成素（LH）和促卵泡生成素（FSH）与精液分析结果进行了比较。在所研究的三组中，睾酮水平相似。少精子症和无精子症组的FSH显著升高（p<0.01）。正常精子症组和少精子症组的LH相似，但无精子症组的LH显著升高（p<0.01）。FSH的升高符合精子发生成熟阶段抑制素释放的理论。LH的升高可能表明存在一种由精子发生早期介导的独立反馈机制，而非仅由睾酮介导。