Andrassy R J, Mahour G H, Isaacs H, Ramon R O, Sosowsky J, Magas D
Am Surg. 1981 Aug;47(8):368-72.
Seventy-five Simonson albino male rates, each weighing 200-300 grams, were randomly divided into five groups of fifteen rats each. Group I, the controls, received rat chow which provided a calorie/nitrogen ratio of 95 Kcal/gram/nitrogen. Animals in Groups II to V received an elemental diet with calorie/nitrogen ratios of 100, 150, 300 and 450 Kcal/gram/nitrogen each, respectively. During the 30-day experimental period, daily calorie intakes were recorded and the rats were weighed every third day. Pre- and post-treatment hepatic function and fatty infiltration were analyzed and compared. The animals treated with a calorie/nitrogen ratio of 100-150 calories/gram of nitrogen had a statistically significant better weight gain with less fatty infiltration of the liver when compared to the other groups. This study supports the clinical impression that administration of lower calorie/nitrogen ratios is associated with a better weight gain.
75只体重为200 - 300克的西蒙森白化雄性大鼠被随机分为五组，每组15只。第一组为对照组，给予大鼠饲料，其热量/氮比为95千卡/克/氮。第二组至第五组的动物分别接受热量/氮比为100、150、300和450千卡/克/氮的要素饮食。在30天的实验期内，记录每日热量摄入量，每三天称一次大鼠体重。分析并比较治疗前后的肝功能和脂肪浸润情况。与其他组相比，接受热量/氮比为100 - 150千卡/克氮治疗的动物体重增加更显著，肝脏脂肪浸润更少。本研究支持了临床印象，即给予较低的热量/氮比与更好的体重增加有关。
