Tsuzuki N, Imai T, Hotta Y
Nihon Seikeigeka Gakkai Zasshi. 1981 Apr;55(4):387-97.
Characteristics features of the histopathological findings of the ossification of the posterior longitudinal ligament (OPLL) of the cervical spine are as follows: 1. In the segmental type of OPLL, the ossification of fibers usually initiates near the posterior border of the vertebral body and in those fibers which attach to the edge of the vertebral body. 2. At the axial ossifying point, degeneration of fibers occurs and enchondral ossification process follows, while in other part of the ossifying area, different types of ossification processes may also occur. 3. In association with OPLL, especially in the hyperostotic type, other paraspinal soft tissues may exhibit proliferation of the cartilage cells with or without ossification, implying the presence of ossifying tendency of the whole body. Of these tissues, the periosteum, the annulus fibrosus and/or the dura mater demonstrate proliferating changes in direct contact with OPLL, and the involvement of the periosteum precedes the other changes including OPLL, suggesting some influence from the vertebral side over the ossifying process of the paraspinal soft tissues.
颈椎后纵韧带骨化(OPLL)的组织病理学发现的特征如下:1. 在节段型OPLL中,纤维骨化通常始于椎体后缘附近以及附着于椎体边缘的纤维处。2. 在轴向骨化点,纤维发生退变,随后出现软骨内成骨过程,而在骨化区域的其他部分,也可能发生不同类型的骨化过程。3. 与OPLL相关,尤其是在骨质增生型中,其他椎旁软组织可能出现软骨细胞增殖,伴有或不伴有骨化,这意味着全身存在骨化倾向。在这些组织中,骨膜、纤维环和/或硬脑膜与OPLL直接接触时表现出增殖性变化,并且骨膜的受累先于包括OPLL在内的其他变化,提示椎体侧对椎旁软组织骨化过程有一定影响。