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与可摘义齿佩戴相关的口腔黏膜病变

Oral mucosal lesions associated with the wearing of removable dentures.

作者信息

Budtz-Jørgensen E

出版信息

J Oral Pathol. 1981 Apr;10(2):65-80. doi: 10.1111/j.1600-0714.1981.tb01251.x.

Abstract

Lesions of the oral mucosa associated with wearing of removable dentures may represent acute or chronic reactions to microbial denture plaque, a reaction to constituents of the denture base material, or a mechanical denture injury. The lesions constitute a heterogeneous group with regard to pathogenesis. They include denture stomatitis, angular cheilitis, traumatic ulcers, denture irritation hyperplasia, flabby ridges, and oral carcinomas. Denture stomatitis is the most common condition which affects the palatal mucosa in about 50% of wearers of complete or partial removable dentures. Most of the lesions caused by chronic infection (Candida albicans) or mechanical injury whereas allergic reactions to the denture base materials are uncommon. Angular cheilitis (lesions of the angles of the mouth) is characterized by maceration, erythema and crust formation. The prevalence is about 15% among wearers of complete dentures. The lesions have an infectious origin but several local, including prosthetic, or systemic predisposing conditions are usually present. Traumatic ulcers caused by dentures with overextended or unbalanced occlusion are seen in about 5% of denture wearers. Denture irritation hyperplasia, which is caused by chronic injury of the tissue in contact with the denture border, is present in about 12% of denture wearers. Flabby ridge, which is replacement of alveolar bone by fibrous tissue, is present in 10-20%. Finally, there is evidence that chronic injury of the oral mucosa by dentures in rare instances may predispose to development of carcinomas. Most types of lesions are benign and quite symptomless. However, diagnosis may be difficult and the more severe and dramatic tissue reactions to dentures may indicate underlying systemic diseases. In order to prevent or minimize the extent of the lesions, denture wearers should be recalled regularly for an examination of the oral cavity and the dentures. It is important that the examination is carried out by a person who has adequate medical knowledge.

摘要

与可摘义齿佩戴相关的口腔黏膜病变可能代表对微生物义齿菌斑的急性或慢性反应、对义齿基托材料成分的反应或义齿机械性损伤。就发病机制而言,这些病变构成了一组异质性疾病。它们包括义齿性口炎、口角炎、创伤性溃疡、义齿性增生、松软牙槽嵴和口腔癌。义齿性口炎是最常见的情况,约50%的全口或部分可摘义齿佩戴者的腭黏膜会受到影响。大多数病变是由慢性感染(白色念珠菌)或机械损伤引起的,而对义齿基托材料的过敏反应并不常见。口角炎(嘴角病变)的特征是浸渍、红斑和结痂形成。在全口义齿佩戴者中,患病率约为15%。这些病变有感染性起源,但通常存在几种局部因素,包括修复因素或全身易感因素。约5%的义齿佩戴者会出现由义齿过度伸展或咬合不平衡引起的创伤性溃疡。义齿性增生是由与义齿边缘接触的组织慢性损伤引起的,约12%的义齿佩戴者会出现这种情况。松软牙槽嵴是由纤维组织替代牙槽骨形成的,发生率为10%-20%。最后,有证据表明,义齿对口腔黏膜的慢性损伤在极少数情况下可能易引发癌症。大多数类型的病变是良性的,且相当无症状。然而,诊断可能困难,对义齿更严重、更显著的组织反应可能表明潜在的全身性疾病。为了预防或最小化病变的程度,应定期召回义齿佩戴者检查口腔和义齿。由具备足够医学知识的人员进行检查很重要。

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