's-Gravenmade E J, Wemes J C, Dankert J
Oral Surg Oral Med Oral Pathol. 1981 Jul;52(1):97-100. doi: 10.1016/0030-4220(81)90180-8.
Quantitative measurements with Schiff reagent of the diffusion of aldehydes from endodontically prepared teeth were performed as a function of time, quantity, and concentration of the inserted drug, repeated sealing of the drug in the root canal, the age of the tooth, and the site of the diffusion. The measurements are based on the reaction of aldehydes with Schiff reagent. All teeth were permeable to formaldehyde-containing drugs. Diffusion of the formaldehyde could be detected within 1 minute. The bulk of the inserted formaldehyde diffused through the apical third, but in young teeth (less than 20 years) the whole root surface was permeable. A 2 percent solution of glutaraldehyde, unlike 10 and 25 percent studies, tended to permeate through the dentin and cementum.
使用席夫试剂对根管预备后的牙齿中醛类物质的扩散进行定量测量，测量结果作为插入药物的时间、数量、浓度、在根管中重复封药情况、牙齿年龄以及扩散部位的函数。这些测量基于醛类物质与席夫试剂的反应。所有牙齿对含甲醛药物均具有渗透性。甲醛在1分钟内即可被检测到扩散。插入的大部分甲醛通过根尖三分之一扩散，但在年轻牙齿（小于20岁）中，整个牙根表面都具有渗透性。与10%和25%的戊二醛溶液研究不同，2%的戊二醛溶液倾向于透过牙本质和牙骨质。
