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无临床癫痫的儿童局灶性癫痫性脑电图放电:病因、临床意义及处理

Focal epileptic EEG discharges in children not suffering from clinical epilepsy: etiology, clinical significance, and management.

作者信息

Lerman P, Kivity-Ephraim S

出版信息

Epilepsia. 1981 Oct;22(5):551-8. doi: 10.1111/j.1528-1157.1981.tb04126.x.

DOI:10.1111/j.1528-1157.1981.tb04126.x
PMID:6793352
Abstract

Epileptic discharges in the EEG record may be found in children not suffering from convulsive seizures. Such discharges often consist of spiking in the rolandic and midtemporal areas (labelled centrotemporal spikes) and less often in the occipital region. They may be multifocal. These focal discharges seem to be age-dependent, tending to disappear during the teenage years. Children displaying such discharges are discovered either through large-scale EEG studies of asymptomatic children or among those who are referred for EEG because of various nonrelated complaints such as headaches, bed-wetting, syncope, behaviour problems, and learning difficulties. Many of them are labelled as suffering from "masked epilepsy" and are considered as epileptics. One hundred such cases are reviewed, and the clinical and EEG data are analysed. Three illustrative case reports are presented, and the literature is critically reviewed. It is maintained that these children are not to be considered as epileptic and should not be treated with anticonvulsant drugs.

摘要

脑电图记录中的癫痫放电可能出现在未患惊厥性癫痫发作的儿童中。此类放电通常表现为中央颞区(标记为中央颞棘波)的棘波,枕区出现的情况较少。它们可能是多灶性的。这些局灶性放电似乎与年龄有关,在青少年时期往往会消失。显示此类放电的儿童要么是通过对无症状儿童进行大规模脑电图研究发现的,要么是在因头痛、尿床、晕厥、行为问题和学习困难等各种无关主诉而接受脑电图检查的儿童中发现的。他们中的许多人被标记为患有“隐匿性癫痫”,并被视为癫痫患者。本文回顾了100例此类病例,并分析了临床和脑电图数据。给出了三个典型病例报告,并对相关文献进行了批判性综述。本文认为,这些儿童不应被视为癫痫患者,也不应使用抗惊厥药物进行治疗。

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Focal epileptic EEG discharges in children not suffering from clinical epilepsy: etiology, clinical significance, and management.无临床癫痫的儿童局灶性癫痫性脑电图放电:病因、临床意义及处理
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引用本文的文献

1
Dipole source analysis of rolandic spikes in benign rolandic epilepsy and other clinical syndromes.良性中央回癫痫及其他临床综合征中中央回棘波的偶极子源分析
Brain Topogr. 1993 Spring;5(3):203-13. doi: 10.1007/BF01128988.
2
Benign partial epilepsy and related conditions: multifactorial pathogenesis with hereditary impairment of brain maturation.
Eur J Pediatr. 1989 Dec;149(3):152-8. doi: 10.1007/BF01958268.