Evidence of thyrotropin-releasing hormone activity in autopsy pancreata from newborns.

Pancreata, obtained from infants who had died during the neonatal period, were pooled and extracted with methanol. The extracts were submitted to cation exchange and high pressure liquid chromatography. The fractions were assayed for TRH by RIA and a mouse bioassay. The results indicate that the pancreata of newborns contain TRH.