Nenci G G, Agnelli G, De Cunto M, Gresele P
Acta Haematol. 1981;66(2):117-21. doi: 10.1159/000207108.
Three infusions of vincristine-loaded platelets were carried out in a young man with acute idiopathic thrombocytopenic purpura (ITP) refractory to steroids. This procedure, used until now only for chronic refractory ITP, insured a remission without side effects. After 2 years of follow-up the patient has not had relapse. A potentially dangerous splenectomy was thus avoided in a phase of the disease in which a spontaneous remission was still very probable.
对一名患有急性特发性血小板减少性紫癜(ITP)且对类固醇治疗无效的年轻男性进行了三次加载长春新碱的血小板输注。该程序此前仅用于慢性难治性ITP,确保了缓解且无副作用。经过2年的随访,患者未复发。因此,在疾病的一个阶段避免了可能危险的脾切除术,而此时仍很有可能出现自发缓解。