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[临界性原发性高血压与肾上腺素能神经系统。鉴定试验]

[Borderline essential hypertension and the adrenergic nervous system. Identification assay].

作者信息

Cuche J L, Guédon J

出版信息

Arch Mal Coeur Vaiss. 1981 Jun;74 Spec No:107-15.

PMID:6794524
Abstract

The physiopathological participation of the sympathetic nervous system in borderline hypertension may be assessed on the following criteria: I) A quantitative rather than qualitative classification of hypertensive patients shows a group of patients with diastolic pressures between 75 and 95 mm Hg, in whom increases in cardiac output are closely related to increases in heart rate; 2) Clinical examination, which should include an assessment of personality, shows a higher incidence of signs in favour of an increase (absolute or relative) in sympathetic activity; 3) Plasma catecholamine levels are not helpful: the absence of raised concentrations could be related to increased excretion, especially by the kidney; 4) Urinary excretion of catecholamines is slightly raised: this is very evident when homovanillic acid levels are assessed.

摘要

交感神经系统在临界高血压中的生理病理参与情况可依据以下标准进行评估

I)对高血压患者进行定量而非定性分类时,会发现一组舒张压在75至95毫米汞柱之间的患者,其心输出量的增加与心率的增加密切相关;2)临床检查,其中应包括对人格的评估,显示出有利于交感神经活动增加(绝对或相对)的体征发生率更高;3)血浆儿茶酚胺水平并无帮助:浓度未升高可能与排泄增加有关,尤其是通过肾脏;4)儿茶酚胺的尿排泄略有升高:当评估高香草酸水平时,这一点非常明显。

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