Petrus M, Claverie J, Vancina S, Becue J, Dutau G, Rochiccioli P
Arch Fr Pediatr. 1981 Jun-Jul;38(6):417-22.
Clinical, biological and anatomic studies were performed in 6 adolescent girls with the Stein-Leventhal syndrome. The rare occurrence of this syndrome in pediatrics is emphasized. The main clinical signs consist of obesity, hirsutism and menstrual irregularities. Basic LH and plasma testosterone are useful diagnostic means, as well as -- in children -- the suppression-stimulation and LH-RH tests. However, coelioscopy is necessary to allow a correct diagnosis. Histological examination might not be absolutely necessary since a large biopsy could be responsible for untimely ovulation. Estrogens and anti-androgens are the only logical treatment at the time of puberty.
对6名患有斯坦因-莱文塔尔综合征的青春期女孩进行了临床、生物学和解剖学研究。强调了该综合征在儿科的罕见性。主要临床体征包括肥胖、多毛症和月经不调。基础促黄体生成素(LH)和血浆睾酮是有用的诊断手段,在儿童中,抑制-刺激试验和促性腺激素释放激素(LH-RH)试验也是如此。然而,腹腔镜检查对于做出正确诊断是必要的。组织学检查可能并非绝对必要,因为大的活检可能导致过早排卵。在青春期,雌激素和抗雄激素是唯一合理的治疗方法。