革兰氏阳性菌mRNA的起始因子非依赖性翻译
Initiation factor-independent translation of mRNAs from Gram-positive bacteria.
作者信息
McLaughlin J R, Murray C L, Rabinowitz J C
出版信息
Proc Natl Acad Sci U S A. 1981 Aug;78(8):4912-6. doi: 10.1073/pnas.78.8.4912.
Abstract
Initiation factor-independent translation of mRNA derived from bacillus phage phi29 DNA occurs with translation systems derived from Bacillus subtilis or Escherichia coli. This is in sharp contrast to the strict dependence on ribosome salt wash fraction of E. coli ribosomes for the translation of T7 and other mRNAs derived from Gram-negative organisms.
摘要
源自芽孢杆菌噬菌体φ29 DNA的mRNA可通过源自枯草芽孢杆菌或大肠杆菌的翻译系统进行不依赖起始因子的翻译。这与严格依赖大肠杆菌核糖体的核糖体盐洗组分来翻译T7及其他源自革兰氏阴性菌的mRNA形成了鲜明对比。
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