Levinson M L, Lynch J P, Bower J S
Am J Med. 1981 Nov;71(5):908-12. doi: 10.1016/0002-9343(81)90397-1.
Hypersensitivity pneumonitis secondary to gold therapy has been described in only a limited number of patients. The clinical presentation is variable and optimal therapy is not well established. Two patients presenting with life-threatening respiratory insufficiency that progressed despite discontinuation of gold therapy are described. Dramatic improvement occurred following corticosteroid administration. Review of previously reported cases shows corticosteroid therapy to be efficacious. Patients with gold hypersensitivity pneumonitis may have a fulminant course and many require corticosteroids for relief.
继发于金制剂治疗的超敏性肺炎仅在少数患者中被描述过。其临床表现多样，最佳治疗方法尚未明确。本文描述了两名患者，尽管停用了金制剂治疗，但仍出现危及生命的呼吸功能不全且病情进展。给予皮质类固醇治疗后病情显著改善。对既往报道病例的回顾显示皮质类固醇治疗有效。金超敏性肺炎患者可能病情凶险，许多患者需要使用皮质类固醇来缓解症状。
