Serradimigni A, Mathieu P, Leonetti J, Franck R, Arnoux F, Egre A
Arch Mal Coeur Vaiss. 1981 Oct;74(10):1197-203.
Selective angiopneumography is considered to be the best diagnostic investigation for pulmonary embolism. However, the technique has to be performed in a specialised unit, is associated with a certain degree of risk and does not explore the lower limb veins which are the usual site of migratory thrombi. The authors have therefore developed a new angiographic technique, ascending venous angiopneumography (AVAP) which successively opacifies the lower limb veins, inferior vena cava (IVC) and pulmonary arteries. It was used in 180 patients suspected of having a recent pulmonary embolism. It has three main advantages: 1) TECHNIQUE: this only involves injection of a vein on the dorsum of the foot, may be carried out in any radiological centre and is repeatable. 2) DIAGNOSIS: the investigation is more sensitive but less specific than selective angiopneumography when compared in a series of 25 cases: it was never normal in the 16 cases of pulmonary embolism, but in its absence there were 4 doubtful cases out of 8. This lack of specificity is compensated by the data obtained during the initial phlebocavographic times. The diagnosis of pulmonary embolism may be made when the context is suggestive and radiological evidence of venous thrombosis is obtained (124 cases). The diagnosis is very improbable when all phases of AVAP are normal (45 cases). 3) THERAPY: treatment should take the initial venous thrombosis into account, especially with regards to the choice of thrombolytic agents and surgical clipping of the IVC. Finally, this is a low-risk procedure.
选择性血管造影被认为是诊断肺栓塞的最佳检查方法。然而,该技术必须在专门的科室进行,存在一定程度的风险,并且无法探查下肢静脉,而下肢静脉是游走性血栓的常见部位。因此,作者开发了一种新的血管造影技术,即上行静脉血管造影(AVAP),它可以依次使下肢静脉、下腔静脉(IVC)和肺动脉显影。该技术应用于180例疑似近期发生肺栓塞的患者。它具有三个主要优点:1)技术:仅需在足背静脉注射,可在任何放射科进行,且可重复操作。2)诊断:在25例病例的系列比较中,该检查比选择性血管造影更敏感但特异性较低:在16例肺栓塞病例中检查结果从未正常,但在无肺栓塞的8例中有4例结果可疑。最初静脉腔静脉造影阶段获得的数据弥补了这种特异性的不足。当临床情况提示且获得静脉血栓形成的影像学证据时(124例),可作出肺栓塞的诊断。当AVAP的所有阶段均正常时(45例),肺栓塞的诊断极不可能成立。3)治疗:治疗应考虑最初的静脉血栓形成,特别是在选择溶栓药物和IVC手术夹闭方面。最后,这是一种低风险的操作。