Edwards M S, Levin V A, Seager M L, Wilson C B
Childs Brain. 1981;8(6):444-51. doi: 10.1159/000120013.
Cerebrospinal fluid dissemination of medulloblastoma occurs despite adequate systemic chemotherapy, and unless it is present at the time of initial diagnosis, occurs late in the course of the disease. Intrathecal chemotherapy with an implanted Ommaya reservoir can produce short-term benefit. We report here our protocol for and the results of intrathecal chemotherapy for leptomeningeal dissemination of medulloblastoma.
尽管进行了充分的全身化疗，髓母细胞瘤仍会发生脑脊液播散，除非在初始诊断时就已存在，否则会在疾病进程的后期出现。使用植入式Ommaya储液器进行鞘内化疗可产生短期益处。我们在此报告我们针对髓母细胞瘤软脑膜播散的鞘内化疗方案及结果。
