Effect of non-steroidal anti-inflammatory drugs on arachidonic acid metabolism.
作者信息
Siegel M I
出版信息
Headache. 1981 Nov;21(6):264-71. doi: 10.1111/j.1526-4610.1981.hed2106264.x.
Abstract
摘要
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Effect of non-steroidal anti-inflammatory drugs on arachidonic acid metabolism.
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Aspirin-like drugs interfere with arachidonate metabolism by inhibition of the 12-hydroperoxy-5,8,10,14-eicosatetraenoic acid peroxidase activity of the lipoxygenase pathway.阿司匹林样药物通过抑制脂氧合酶途径中12-氢过氧-5,8,10,14-二十碳四烯酸过氧化物酶的活性来干扰花生四烯酸代谢。
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