Kigawa J
Nihon Sanka Fujinka Gakkai Zasshi. 1981 Oct;33(10):1646-54.
The values of pO2 and pCO2 were determined in the uterine cavity by a medical mass spectrometer (MEDSPECT-MS80) in 45 cases of uterine myoma, 26 cervical carcinoma, 6 endometrial carcinoma and 20 normal uterus cases. The uterine tissue pO2 and pCO2 correlated with the pO2 and pCO2 determined in the uterine cavity or cervical canal. No statistically significant change of pO2 nor pCO2 was noted between the values of uterine cavity and cervical canal. The pO2 was higher and pCO2 was lower in the luteal phase than proliferative in 7 menstrual cycles. The mean values of intracavitary pO2 and pCO2 were 22.5 +/- 5.3 mmHg, 53.5 +/- 5.1 mmHg respectively in the cases of uterine myoma, 23.6 +/- 5.6 mmHg, 60.7 +/- 7.6 mmHg in cervical carcinoma, 20.8 +/- 1.0 mmHg, 54.5 +/- 3.7 mmHg in endometrial carcinoma and 28.5 +/- 4.3 mmHg, 53.5 +/- 5.1 mmHg in normal control uterus respectively. The intracavitary pO2 was lower and pCO2 was higher in the cases of uterine neoplasm than the control, and particularly the pCO2 was significantly higher in cervical carcinoma than the control.
采用医用质谱仪(MEDSPECT-MS80)测定了45例子宫肌瘤、26例宫颈癌、6例子宫内膜癌及20例正常子宫病例的宫腔内氧分压(pO2)和二氧化碳分压(pCO2)。子宫组织的pO2和pCO2与宫腔或宫颈管内测定的pO2和pCO2相关。宫腔和宫颈管内的pO2及pCO2值之间未观察到统计学上的显著变化。在7个月经周期中,黄体期的pO2较高而pCO2较低,相比增殖期。子宫肌瘤病例宫腔内pO2和pCO2的平均值分别为22.5±5.3 mmHg、53.5±5.1 mmHg;宫颈癌病例分别为23.6±5.6 mmHg、60.7±7.6 mmHg;子宫内膜癌病例分别为20.8±1.0 mmHg、54.5±3.7 mmHg;正常对照子宫病例分别为28.5±4.3 mmHg、53.5±5.1 mmHg。子宫肿瘤病例的宫腔内pO2低于对照组,pCO2高于对照组,尤其是宫颈癌的pCO2显著高于对照组。