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Pure red cell aplasia associated with sodium valproate therapy.

作者信息

MacDougall L G

出版信息

JAMA. 1982 Jan 1;247(1):53-4.

PMID:6796707
Abstract

Pure red cell aplasia developed in a 9-year-old girl receiving sodium valproate therapy. Infection with measles and chickenpox had occurred two months previously. Regeneration of bone marrow erythroid precursors was demonstrated one month after drug withdrawal. Readministration of sodium valproate resulted in a second episode of red cell aplasia that again resolved promptly after drug withdrawal. The respective roles of infection and drugs in the etiology of red cell aplasia are discussed.

摘要

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Pure red cell aplasia associated with sodium valproate therapy.
JAMA. 1982 Jan 1;247(1):53-4.
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2
Pure red cell aplasia after 13 years of sodium valproate, and bone marrow suppression after 17 years of carbamazepine.服用丙戊酸钠13年后出现纯红细胞再生障碍，服用卡马西平17年后出现骨髓抑制。
PLoS Med. 2004 Nov;1(2):e51. doi: 10.1371/journal.pmed.0010051. Epub 2004 Nov 30.
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Haematological disturbances during long-term valproate therapy.
长期丙戊酸盐治疗期间的血液学紊乱
Eur J Pediatr. 1994 May;153(5):378-80. doi: 10.1007/BF01956425.
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Fatal pancytopenia during high-dose valproate monotherapy.高剂量丙戊酸单药治疗期间出现的致命性全血细胞减少症。
Eur J Pediatr. 1992 Aug;151(8):619. doi: 10.1007/BF01957735.