Carpenter S, Karpati G
Neurology. 1981 Dec;31(12):1564-8. doi: 10.1212/wnl.31.12.1564.
Skin biopsies of three patients with Lafora disease (clinically typical and proven by liver biopsy) showed PAS-positive inclusions in numerous peripheral cells of eccrine sweat ducts. By electronmicroscopy, the inclusions consisted of polyglucosan-type material; they were not bounded by a membrane. Skin biopsy should be a convenient method of diagnosing Lafora disease.
三名患有拉福拉病（临床症状典型且经肝活检证实）患者的皮肤活检显示，外分泌汗腺导管的许多外周细胞中存在PAS阳性包涵体。通过电子显微镜观察，这些包涵体由多聚葡萄糖类型的物质组成；它们没有膜包裹。皮肤活检应该是诊断拉福拉病的一种便捷方法。
