Grebe S F, Weise M, Berghäuser H, Fängewisch G L, Temme H
Radiologe. 1981 Dec;21(12):553-61.
81 patients with renal abnormalities or renal disorders of different genesis and severity with and without restricted renal function were investigated by means of the classical PAH- and inulin-clearance. Furthermore a radioisotope nephrography was carried out after application of I 131-Hippuran followed by Cr 51-EDTA. In addition the activity reduction was measured above the shoulder, as well as the activity in serum samples and urine samples gained 30 min after application. A comparison of the clearance values found with those of conventional clearance resulted in poor correlation for I 131-Hippuran (r = 0.54) and no correlation for Cr51-EDTA. Of the many parameters of the radioisotope nephrogram curves only the following are able to give sufficient quantitative functional results: The parameters connected with the rise of the curve between the 48rh and 120rh s and those connected with the slope of the secant. This is also true for the values of activity measured in the urine.
81例患有不同病因和严重程度的肾脏异常或肾脏疾病的患者，无论其肾功能是否受限，均通过经典的对氨基马尿酸（PAH）清除率和菊粉清除率进行研究。此外，在应用碘131 - 马尿酸后接着应用铬51 - 乙二胺四乙酸（Cr 51 - EDTA）进行放射性核素肾造影。另外，还测量了给药后30分钟时肩部上方的放射性活度降低情况以及血清样本和尿液样本中的放射性活度。将所测得的清除率值与传统清除率值进行比较，结果显示碘131 - 马尿酸的相关性较差（r = 0.54），而铬51 - EDTA则无相关性。在放射性核素肾图曲线的众多参数中，只有以下参数能够给出足够的定量功能结果：与曲线在第48秒至120秒之间上升相关的参数以及与割线斜率相关的参数。尿液中测得的放射性活度值也是如此。
