三种倍半萜内酯对枯草芽孢杆菌修复缺陷型突变体的DNA损伤作用。
DNA damaging effects of three sesquiterpene lactones in repair-deficient mutants of Bacillus subtilis.
作者信息
Jones D H, Kim H L, Donnelly K C
出版信息
Res Commun Chem Pathol Pharmacol. 1981 Oct;34(1):161-4.
PMID:6797005
Abstract
Three sesquiterpene lactones (hymenoxon, helenalin, and tenulin) were tested for genotoxicity using six strains of Bacillus subtilis. Hymenoxon was found to produce lethal DNA damage in strains rec A8 and mc-1 while helenalin was lethal in strains mc-1 and rec E4. Tenulin did not produce lethal DNA damage in any of the strains tested.
摘要
使用六株枯草芽孢杆菌测试了三种倍半萜内酯（氢化木香内酯、堆心菊灵和苦艾素）的遗传毒性。发现氢化木香内酯在rec A8和mc-1菌株中产生致死性DNA损伤，而堆心菊灵在mc-1和rec E4菌株中具有致死性。苦艾素在任何测试菌株中均未产生致死性DNA损伤。
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