Nazarov I P, Prugov V I
Vestn Khir Im I I Grek. 1981 Oct;127(10):125-8.
The investigation of oxygen exchange in 70 patients operated on the organs of the abdominal cavity has shown that pronounced disturbances of the function of external ventilation and gas exchange are developing in patients in the postoperative period. The application of prolonged ganglionic blockade with normotony by pentamine both during operation and within 5 postoperative days promoted the improvement of oxygen exchange at the level of lungs and tissues. The authors believe that it prevents hyperreaction of the sympatho-adrenal system and adrenals upon the operation trauma, disturbances of the blood microcirculation and the development of metabolic alkalosis in the postoperative period.
对70例接受腹腔器官手术患者的氧交换情况进行的调查显示，患者在术后出现了明显的外呼吸和气体交换功能障碍。在手术期间及术后5天内应用五胺进行长时间的神经节阻滞并维持血压正常，促进了肺和组织水平氧交换的改善。作者认为，这可防止术后交感 - 肾上腺系统和肾上腺对手术创伤产生过度反应、血液微循环紊乱以及代谢性碱中毒的发生。
