Siems W, Müller M, Dumdey R, Holzhütter H G, Rathmann J, Rapoport S M
Acta Biol Med Ger. 1981;40(4-5):703-6.
The shares of glucose utilizing processes in red blood cells under aerobic conditions were estimated in tracer experiments and with mathematical methods. A complex method of these pathways in reticulocytes is given. Our approach to the solution of the problem in reticulocytes can be transferred to other tissues. The new mathematical technique used is suitable for derivation of closed terms for the specific radioactivity of single positions of C-atoms of the metabolites of citrate cycle. Therefore, by means of regressions analysis, the calculation of unknown concentrations and flux rates is possible.
在示踪实验中并采用数学方法估算了有氧条件下红细胞中葡萄糖利用过程的份额。给出了网织红细胞中这些途径的复杂方法。我们解决网织红细胞中该问题的方法可应用于其他组织。所采用的新数学技术适用于推导柠檬酸循环代谢物C原子单个位置比放射性的封闭项。因此，通过回归分析，可以计算未知浓度和通量率。
