[Transitory IgM monoclonal gammopathy associated with brucellosis and tuberculosis (author's transl)].

Two cases of transitory IgM monoclonal gammopathy associated with infectious disease are presented. One patient was a 29 year-old woman with acute brucellosis; electrophoresis showed a homogeneous spike of slow gamma mobility constituted of IgM lambda. The second case was a 52 year-old male with milliary tuberculosis, in whom a homogenous spike of rapid gamma mobility constituted of IgM kappa was found. The monoclonal component disappeared in both cases after treatment of the infections; at 2 and 21/2 months respectively. The fact that the association of transitory IgM paraprotein and infection is not common, especially with brucellosis, is commented upon and a direct relationship between the infection and the monoclonal component is suggested.