Schumann J, Schulz F
Med Klin. 1981 Dec 18;76(26):738-42.
The postoperative secretion rate of TSH before and after stimulation by TRF was studied in 43 patients with hyperfunctioning thyroid adenomas. TSH secretion is reduced and not at all or insufficiently stimulated by TRF preoperatively. This condition normalizes six weeks after operation. Mainly in those patients, who needed extensive resections of thyroid parenchyma basal TSH concentration and stimulation by TRF were elevated postoperatively. Following enucleations of adenomas or small resections we do not perform a substitution therapy, but control TSH-secretion rates in yearly intervals.
对43例甲状腺功能亢进性腺瘤患者术后促甲状腺激素(TSH)在促甲状腺激素释放因子(TRF)刺激前后的分泌率进行了研究。术前TSH分泌减少,TRF对其无刺激作用或刺激作用不足。术后六周这种情况恢复正常。主要是那些需要广泛切除甲状腺实质的患者,术后基础TSH浓度和TRF刺激后升高。腺瘤摘除术或小范围切除术后,我们不进行替代治疗,而是每年监测TSH分泌率。