Markand O N, Garg B P, Brandt I K
Neurology. 1982 Feb;32(2):151-6. doi: 10.1212/wnl.32.2.151.
Five patients with nonketotic hyperglycinemia had serial EEGs and evoked-response studies. EEGs were grossly abnormal in all patients. In the neonatal period, the "suppression-burst" pattern was observed. The EEG changed to hypsarrhythmia during early or mid-infancy. In the second to fifth years of life, multifocal epileptiform discharges superimposed on diffuse slow background activity constituted the usual abnormality during wakefulness, but more severe disorganization of the EEG occurred in sleep with emergence of hypsarrhythmia. Four patients had abnormal brainstem auditory evoked responses, characterized by prolongation of I-V interval, and two had abnormal flash-induced visual evoked responses.
五名非酮症高甘氨酸血症患者接受了系列脑电图（EEG）和诱发电位研究。所有患者的脑电图均明显异常。在新生儿期，观察到“抑制-爆发”模式。脑电图在婴儿早期或中期转变为高度节律失调。在生命的第二年至第五年，清醒时通常的异常表现为多灶性癫痫样放电叠加在弥漫性慢波背景活动上，但睡眠时脑电图出现更严重的紊乱，伴有高度节律失调。四名患者脑干听觉诱发电位异常，表现为I-V间期延长，两名患者闪光诱发视觉诱发电位异常。
