Wood P R, McKee K T, Lohr J A, Hendley J O
JAMA. 1982 Feb 26;247(8):1162-3.
The relative frequency of meningitis caused by Haemophilus influenzae in school-age children was determined by reviewing etiologic diagnoses in children 6 to 15 years old admitted to four hospitals from 1974 to 1978. Sixty-five (45%) of 145 patients had aseptic meningitis and 29 (20%) had bacterial meningitis. Thirty-two (22%) of the patients had received antibiotic therapy before diagnosis, and 19 (13%) could not be classified. Six (21%) of the 29 patients with bacterial meningitis had H influenzae meningitis. Although aseptic disease was the most common type of meningitis, initial antibiotic therapy for presumed bacterial meningitis in school-aged children should include adequate coverage for H influenzae.
通过回顾1974年至1978年期间入住四家医院的6至15岁儿童的病因诊断，确定了学龄儿童中由流感嗜血杆菌引起的脑膜炎的相对发生率。145名患者中有65名（45%）患有无菌性脑膜炎，29名（20%）患有细菌性脑膜炎。32名（22%）患者在诊断前接受了抗生素治疗，19名（13%）无法分类。29名细菌性脑膜炎患者中有6名（21%）患有流感嗜血杆菌脑膜炎。尽管无菌性疾病是最常见的脑膜炎类型，但学龄儿童疑似细菌性脑膜炎的初始抗生素治疗应包括对流感嗜血杆菌的充分覆盖。
